業績

Journal Papers

  • Sakumura Y, Koyama Y, Tokutake H, Hida T, Sato K, Itoh T, Akamatsu T, Shin W, Diagnosis by volatile organic compounds in exhaled breath from lung cancer patients using support vector machine algorithm. Sensors, 17, 287, doi:10.3390/s17020287, 2017.

<li>Okimura C, Ueda K, Sakumura Y and Iwadate Y, Fast-crawling cell types migrate to avoid the direction of periodic substratum stretching. <a href="http://www.tandfonline.com/doi/full/10.1080/19336918.2015.1129482" target="_blank">Cell Adhesion &amp; Migration</a>, DOI:10.1080/19336918.2015.1129482, 2016.</li>

<li>Katsuno H, Toriyama M, Hosokawa Y, Mizuno K, Ikeda K, Sakumura Y, Inagaki N. Actin Migration Driven by Directional Assembly and Disassembly of Membrane-Anchored Actin Filaments, <a href="http://www.cell.com/cell-reports/abstract/S2211-1247(15)00674-9" target="_blank">Cell Reports</a>, 12, 1–13, 2015.</li>

<li>Fujimuro T, Matsui T, Nitanda Y, Matta T, Sakumura Y, Saito M, Kohno K, Nakahata Y, Bessho Y, Hes7 3′UTR is required for somite segmentation function, Scientific Reports, doi:10.1038/srep06462, 2014.</li>

<li>Pham TM, Tan KW, Sakumura Y, Okumura K, Maki H, Akiyama MT. A single-molecule approach to DNA replication in

Escherichia coli cells demonstrated that DNA polymerase III

is a major determinant of fork speed, Mol. Microbiol. doi:10.1111/mmi.12386, 2013</li>

<li>Kozawa S, Sakumura Y, Toriyama M, Inagaki N, Ikeda K. Bayesian Cell Force Estimation Considering Force Directions, Neural Processing Letters, DOI 10.1007/s11063-013-9320-y, 2013</li>

<li>Toriyama M, Kozawa S, Sakumura Y, Inagaki N, Conversion of a Signal into Forces for Axon Outgrowth through Pak1-mediated Shootin1 Phosphorylation, Curr. Biol. 23, 529–534, 2013.</li>

<li>Kaneko-Kawano T, Takasu F, Naoki H, Sakumura Y, Ishii S, Ueba T, Eiyama A, Okada A, Kawano Y, Suzuki K. Dynamic Regulation of Myosin Light Chain Phosphorylation by Rho-kinase. PLoS ONE 7(6): e39269. 2012.</li>

<li>Kim W, Matsui T, Yamao M, Ishibashi M, Tamada K, Takumi T, Kohno K, Oba S, Ishii S, *Sakumura Y, and *Bessho Y, The period of the somite segmentation clock is sensitive to Notch activity, Mol. Biol. Cell, 22:18 3541-3549, 2011. (*corresponding authors)</li>

<li>Inagaki N, Toriyama M, Sakumura Y, Systems Biology of Symmetry-Breaking during Neuronal Polarity Formation, Dev. Neurobiol., 71(6), 584-593, 2011.</li>

<li>Toriyama M, *Sakumura Y, Shimada T, Ishii S, *Inagaki N, A Diffusion-based neurite length sensing mechanism involved in neuronal symmetry-breaking, Mol. Syst. Biol., 6:394, 2010. (*corresponding authors)</li>

<li>Hayashi S, Shimoda T, Nakajima M, Tsukada Y, Sakumura Y, Dale JK, Maroto M, Kohno K, Matsui T, Bessho Y. Sprouty4, an FGF inhibitor, displays cyclic gene expression under the control of the notch segmentation clock in the mouse PSM. PLoS One. 4(5):e5603, 2009.</li>

<li>Tsukada Y, Aoki K, Nakamura T, Sakumura Y, Matsuda M, Ishii S. Quantification of local morphodynamics and local GTPase activity by edge evolution tracking. PLoS Comput. Biol., 4(11): e1000223, 2008.</li>

<li>Honda N, Sakumura Y, Ishii S. Stochastic Control of Spontaneous Signal Generation for Gradient Sensing in Chemotaxis. J. Theor. Biol., 255, 259-266, 2008.</li>

<li>Toriyama M, Shimada T, Kim KB, Mitsuba M, Nomura E, Katsuta K, Sakumura Y, Roepstorff P, Inagaki N. Shootin1: A protein involved in the organization of an asymmetric signal for neuronal polarization. J. Cell Biol. 175(1), 147-157, 2006.</li>

<li>Igarashi Y, *Sakumura Y, and Ishii S. The role of short-term depression in sustained neural activity in the prefrontal cortex: A simulation study. Neural Networks, 19, 1137-1152, 2006. (*corresponding author)</li>

<li>Sakumura Y. and Ishii S. Stochastic Resonance with Differential Code in Feedforward Network with Intra-layer Random Connections. Neural Networks, 19, 469-476, 2006.</li>

<li>Naoki H, Sakumura Y, and Ishii S. Local Signaling with Molecular Diffusion as a Decoder of Ca2+ Signals in Synaptic Plasticity, Mol. Syst. Biol., 1:2005.0027, 2005.</li>

<li>Sakumura Y, Tsukada Y, Yamamoto N, and Ishii S. A Molecular Model for Axon Guidance Based on Crosstalk between Rho GTPases. Biophys. J., 89, pp.812-822, 2005.</li>

<li>Sakumura Y. and Aihara K. Stochastic Resonance and Coincidence Detection in Single Neurons. Neural Processing Letters, 16(3), pp.235-242, 2002.</li>

<li>Sakumura Y, Konno N. and Aihara K. Markov Chain Model Approximating the Hodgkin-Huxley Neuron, Artificial Neural Networks, Lecture Notes in Computer Science, 2130, pp.1153-1160, 2001.</li>

<li>Sakumura Y, Konno N. and Aihara K. Approximating Markov Chain Model of the Hodgkin-Huxley Neuron. Trans. of the Materials Research Society of Japan, 26(1), pp.457-460, 2001.</li>

<li>Sakumura Y. and Aihara K. A Neuronal Time Window for Coincidence Detection. IEICE Transactions on Fundamentals, E81-A(9), pp.1818-1823, 1998.</li>

</ul>

<b>Books &amp; Review Articles</b>

<ul>

<li>Sakumura Y, Inagaki N, Quantitative Modeling of Neuronal Polarization, Technological Advancements in Biomedicine for Healthcare Application, 354-361, IGI global, 2012.</li>

<li>鳥山道則, 作村諭一, 稲垣直之:神経細胞が軸索の長さを検知する仕組みと神経細胞の対称性の破れ, 遺伝, 65, 80-86, 2011.</li>

<li>塚田 祐基, 作村 諭一: 細胞形態変化の定量と現象論的モデル, 細胞工学 339-343, 2010.</li>

<li>石井 信, 作村 諭一: 神経の可塑性と発達の生体反応モデリング. ゲノム情報と生命現象の統合的理解2007, 実験医学増刊(2007年2月), 198-204, 2007.</li>

</ul>

<b>Invited Symposium &amp; Talks</b>

<ul>

<li>Sakumura Y, Inagaki N, Spontaneous Symmetry Breaking in Neural Morphology, Society for Industrial and Applied Mathematics annual meeting 2014, Chicago, 2014.7.7-7.11</li>

<li>Sakumura Y, Okimura C, Iwadate Y, Computational model of directional migration of crawling cell on anisotropic substratum, International Symposium on Mechanobiology 2014, 岡山大学, 2014.5.20-5.23</li>

<li>作村諭一,神経細胞の形態形成モデル, 立命館大学視覚科学統合研究センターシンポジウム, 立命館大学, 2014.3.13-14</li>

<li>作村諭一, 機械学習を用いた細胞内の分子システム同定, 平成25年 電気学会 電子・情報・システム部門大会, 北見工業大学, 2013.9.4-9.7</li>

<li>Sakumura Y, Maeno T, Inagaki N, Irregularity in molecular transport polarizes neuronal morphology, 第65回日本細胞生物学会, ウインクあいち, 2013.</li>

<li>Sakumura Y, Quantitative modeling of cell morphogenesis by Rho family small GTPases, US-Japan Brain Research Cooperative Program, New Orleans, 2012.</li>

<li>作村諭一, 田中大河, 池田和司, 中村岳史, Rho GTPasesによる細胞形態制御の数理モデル, 日本植物学会第76回大会シンポジウム, 兵庫県立大学, 2012.</li>

<li>作村諭一, 実験値と数理による神経形態形成の原理解明に向けて, 東京理科大学生命科学研究所セミナー, 東京理科大学, 2011.</li>

<li>作村諭一, 神経形態形成の定量物理モデル, 神戸大学大学院医学研究科セミナー, 神戸大学, 2010.</li>

<li>作村諭一, 神経細胞の発達における軸索決定過程:定量モデリング, 福井大学大学院工学研究科セミナー, 福井大学, 2009.</li>

<li>Sakumura Y, A quantitative mathematical description of neural polarity, 第31回日本分子生物学会年会シンポジウム, 神戸国際会議場, 2008.</li>

<li>作村諭一, 神経細胞の機能と細胞内空間局所性, 第3回バイオメディカル研究会, 2007</li>

<li>作村諭一, シグナル伝達の拡散と局所性を利用したシナプス可塑性, 2007年度シナプス研究会, 2007.</li>

<li>作村諭一, 神経極性形成における数理モデル, 第17回システムバイオロジー研究会, 2007.</li>

<li>作村諭一, システムバイオロジーとバイオイメージング, 第16回バイオイメージング学会学術集会、16巻2号 p231-232、2007.</li>

<li>作村諭一, 脳・神経機能における入力変動の「度合」の効果、京都大学理学研究科非線形動力学セミナー、2005.</li>

</ul>

<b>International Conference</b>

<ul>

<li>Kozawa S, Sakumura Y, Toriyama M, Inagaki N, Ikeda K, An Estimation of Cell Forces with Hierarchical Bayes Approach Considering Cell Morphology, 19th International Conference on Neural Information Processing (ICONIP 2012), Doha, 501-508, 2012</li>

<li>Sakumura Y. Simulation Analysis of the Network of the Stochastic Spike Generation Model Imitating the Hodgkin-Huxley Neuron, Asia Simulation Conference (JSST2011), 2011.</li>

<li>Yamada T, Jimbo HC, Ishii S, Nishiyama M, Hong K, Sakumura Y. Identification of a molecular system that regulates growth cone membrane potential during growth cone guidance, Computational Neuroscience Society 2011 (CNS*2011), BMC Neuroscience, 12(Suppl 1):280, 2011.</li>

<li>Sakumura Y, Inagaki N. Neural polarization by an economizing system in neurite elongation. EMBO Conference Series on Systems Dynamics of Intracellular Communication (SPATIAL 2011), 2011.</li>

<li>Sakumura Y, A quantitative modeling of neural morphological polarization, Asia Simulation Conference (JSST2009), 2009.</li>

<li>Dauwels J, Tsukada Y, Sakumura Y, Ishii S, Aoki K, Nakamura T, Matsuda M, Vialatte F, Cichocki A. On the synchrony of morphological and molecular signaling events in cell migration. International Conference on Neural Information Processing (ICONIP 2008), 2008.</li>

<li>Tsukada Y, Aoki K, Sakumura Y, Nakamura T, Matsuda M, and Ishii S. Quantitative Morphodynamic Analysis of FRET time-lapse imaging. International Conference on Systems Biology (ICSB 2008), DS2-1-54 pp.104, 2008.</li>

<li>Tsukada, Y., Sakumura, Y., Ishii, S. Quantitative Morphodynamic Analysis of Time-Lapse Imaging by Edge Evolution Tracking. International Conference on Neural Information Processing (ICONIP 2007), 2007.</li>

<li>Naoki, H., Sakumura, Y., and Ishii, S. Spontaneous signal generation induced by reaction noise for gradient sensing in chemotaxis. International Conference of Systems Biology (ICSB 2007), pp.46, 2007.</li>

<li>Sakumura, Y., Tsukada Y., Yamamoto, N., and Ishii, S. Axon guidance based on cross talk between Rho GTPases requires switching mechanism, Society for Neuroscience, 35th Annual Meeting 146.8, 2005.</li>

<li>Igarashi, Y., Sakumura, Y., and Ishii, S. Short-term depression stabilizes sustained neural activities in the prefrontal cortex: a computational study, Society for Neuroscience, 35th Annual Meeting 41.17, 2005.</li>

<li>Sakumura, Y., Tsukada, Y., Yamamoto, N., and Ishii, S. Axon guidance regulated by interactions of Rho family small GTPases. the Sixth International Conference on Systems Biology (ICSB 2005), pp.279, 2005.</li>

<li>Tsukada, Y., Aoki, K., Sakumura, Y., Nakamura, T., Matsuda, M., and Ishii, S. Quantitative Analysis of Morphological Dynamics and the Activity of Rho-family GTPases during Neurite Outgrowth. the Sixth International Conference on Systems Biology (ICSB 2005), pp.316, 2005.</li>

<li>Naoki, H., Sakumura, Y., and Ishii, S. Local signaling with diffusion process as a decorder of Ca2+ signals in synaptic plasticity. The Assembly and Function of Neuronal Circuits. pp.79, 2005.</li>

<li>Igarashi, Y., Sakumura, Y., Ishii, S. The role of short term depression for sustained neural activities in the prefrontal cortex: a simulation study, International Symposium on Nonlinear Theory and its Applications (NOLTA 2004), 509-512, 2004.</li>

<li>Sakumura, Y., Tsukada Y., and Ishii, S. Spike Synchronization Represents Temporal Difference of Neural Population Activity in a Cortical Model. New Horizons in Molecular Sciences and Systems: An Integrated Approach, 51, 2003.</li>

<li>Sakumura, Y. and Ishii, S. The differential operation by neural assembly. 2002 International Symposium on Nonlinear Theory and its Applications, 323-326, 2002.</li>

<li>Sakumura, Y. and Aihara, K. A Simple Neuron Model Approximating Firing Pattern of the Hodgkin-Huxley Neuron, The 7th International Conference on Neural Information Processing (ICONIP 2000), 1291-1294, 2000.</li>

<li>Sakumura, Y. and Aihara, K. A Simplified Single Neuron Model as a Rapid Depolarization Detector Based on the H-H Type Neuron, The 5th International Symposium on Artificial Life and Robotics (AROB 2000), 161-164, 2000.</li>

<li>Sakumura, Y., Konno, N., and Aihara, K. Approximating Markov Chain Model of the Hodgkin-Huxley Neuron, The 12th Symposium of the Materials Research Society of Japan, 213, 2000.</li>

<li>Sakumura, Y. and Aihara, K. Coincidence Detection and Stochastic Resonance, The 4th Tamagawa International Dynamic Brain Forum, 1999.</li>

<li>Sakumura, Y., Konno, N. and Aihara, K. A Role of the EPSP Rising Time Constant for Irregular Firing, Japan-China Symposium on Advanced Information Technology, 199-206, 1999.</li>

<li>Sakumura, Y., Konno, N. and Aihara, K. Irregular Firing of a Modulation Detecting Neuron, The 3rd International Workshop on Neuronal Coding, 93-96, 1999.</li>

<li>Sakumura, Y. and Aihara, K. Stochastic Resonance by a Modulation Detecting Neuron, The 5th International Conference on Neural Information Processing, 951-954, 1998.</li>

<li>Sakumura, Y. and Aihara, K. A Neuronal Time Window for Coincidence Detection, 1997 International Symposium on Nonlinear Theory and Its Applications, 127-130, 1997.</li>

<li>Sakumura, Y. Temporal Coding by Superimposed Periodic Pulses on Active Dendrites, 1995 International Symposium on Nonlinear Theory and Its Applications, 1995.</li>

</ul>